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The cellulosic polymers have a degree of substitution (DS) of their anhydroglucose unit of from greater than 0 up to 3inclusive. Degree of substitution (DS) means the average number of hydroxyl groups originally present on the anhydroglucose unit that are replaced by a substituting group or converted into another group. The anhydroglucose unit can be partially or completely substituted with groups such as acylalkanoyl, alkenoyl, aroyl, alkyl, alkoxy, halogen, carboalkyl, alkylcarbamate, alkylcarbonate, alkylsulfonate, alkysulfamate, semipermeable polymer forming groups, and the like, wherein the organic moieties contain from one to twelve carbon atoms, and preferably from one to eight carbon atoms. The semipermeable compositions typically include a member selected from the group consisting of cellulose acylate, cellulose diacylate, cellulose triacylate, cellulose acetate, cellulose diacetate, cellulose triacetate, mono- di- and tri-cellulose alkanylates, mono- di- and tri-alkenylates, mono- di- and tri- aroylates, and the like.

The United States was involved in the talks, and the Clinton administration signed the treaty. But the Senate, lobbied by agriculture and drug companies, has never approved it. The Bush administration is reviewing whether to pursue ratification.]