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Product Description

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Detailed information

The completed dosage forms permit the delivery of the active agent to the delivery site in the liquid state, thus providing minimal delay in the onset of the desired beneficial effect of the active agent, since the active agent does not have to be initially dissolved or dispersed in the form of microparticles at the site of action. Unlike powder carriers of the prior art which are organic and which are insoluble in aqueous media, the calcium hydrogen phosphate carrier is an inorganic carrier that is soluble in gastric fluids.

Band 15 typically exhibits low water permeability and will prevent that portion of the polymer matrix which it surrounds from imbibing fluid, thus substantially limiting any swelling of polymer matrix 11 at that location. The number, size, and placement of the insoluble bands that are applied onto the surface of the active agent formulation matrix may be varied to adjust the active agent delivery profile and the retention time in the stomach. For example, bands 0. 1 mm to about 12 mm in width, preferably between about 0.

Delays in patient enrollment can result in greater costs and longer trial timeframes. Patients may also suffer adverse medical events or side effects.]