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Product Description

In a second embodiment of the present invention, the dosage form is such that the porous particles can be dispersed in a bioerodible carrier. The bioerodible carrier preferably swells upon imbibing fluid from stomach so as to be retained within the stomach of a subject for a prolonged period of time. The bioerodible carrier preferably comprises a polymer matrix formed of a mixture of a swellable, water soluble polymer that expands when in contact with fluids in the gastric environment and a hydroattractant. The matrix could be formed with a rigid or semi-rigid segment in which swelling of the matrix is constrained to provide a rigid or semi-rigid section in the dosage form that facilitates the dosage form remaining in the stomach of a subject over a prolonged period of time. The rigid or semi-rigid section of hidroxicloroquina generico do viagra dosage form preferably comprises one or more insoluble materials, having low water permeability and formed as a band circumscribing a portion of the surface esomeprazole generic uk viagra the matrix, that along with the banded portion of the polymer matrix forms the rigid or semi-rigid segment of the dosage form. In one form, the dosage form comprises viagrande centro oncologico fiorentino a therapeutically-effective amount of a liquid, active agent formulation sorbed into porous particles, (b) a polymer matrix in which the porous particles are dispersed, the polymer matrix including a high molecular weight, water-soluble polymer and a hydroattractant, the polymer matrix having an outer surface for exposure to the environment of use, and (c) a band of insoluble material circumscribing a portion of the outer surface of the polymer matrix. The hydroattractant is preferably a water- insoluble polymer, and the polymer matrix could further include non-polymeric water-soluble excipients and polymers of molecular weight of less than 10,000 grams per mole. The weight percent of the water soluble, high molecular weight polymer could be about 10 to 50 weight percent and the weight percent of the hydroattractant could be about 5 to 70 weight percent. In another form, the dosage form of this embodiment comprises a unitary compressed dispersion of a liquid, active agent formulation in a plurality of porous particles in a gel-forming, erodible polymer matrix having a first portion that swells in the stomach while maintaining its physical cje jeanne mance viagra for a prolonged period of time and a second, non-erodible, non-gel- forming portion for promoting retention of the dosage form in the stomach over a prolonged period of time.

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